Managing Osteoarthritis with Avocado Soybean Unsaponifiables (ASUs)

Managing Osteoarthritis with Avocado Soybean Unsaponifiables (ASUs)

If you suffer from osteoarthritis, you are probably familiar with the pain and swelling that comes with the breakdown of the cartilage and tissue between your joints. 30 million Americans suffer from this disease and most take prescription drugs to manage their symptoms. In this video, I will discuss recent research on an exciting alternative treatment which not only treats these symptoms but may aid in reversing the tissue damage.

The name of this supplement is a mouthful – avocado soybean unsaponifiables, but let’s call it ASU, just to keep things simple. The first two words should sound familiar, but let me break it down further.

In the video below, Dustin Moore reviews what you need to know about managing osteoarthritis with avocado soybean unsaponifiables. 

If you don’t like the video or want more information, continue reading.

What is ASU?

ASU is made from 1/3 avocado oil and 2/3’s soybean oil. Both of these oils contain special compounds called sterols that are filtered out and removed. Now here is where “unsaponifiable” enters the picture.  This word literally means “cannot be made into soap”, as in, the same soap you use to wash your hands.

So if you mix avocado and soybean oils, and attempt to make soap, there would be a tiny portion leftover that would be the ASU’s. Chemistry lessons aside, we are finding that ASU’s have interesting qualities that may be beneficial for joint pain management.

For those who no longer wish to take prescription or over the counter drugs to manage the pain, there is strong scientific evidence that ASU’s can reduce pain and stiffness, improve joint function, and decrease dependence on painkiller medications.

As studies have shown, ASU appears to block the production of molecules and chemicals that cause the pain, stiffness, and inflammation from osteoarthritis. However, we still don’t know if ASU can reverse joint tissue damage. More research needs to be done, but for pain management, it significantly helps.

Related: GERD (Heartburn) Prevention: 5 Dietary Things To Avoid


ASU dosing and safety

The safe and effective dose is 300 milligrams a day, and you can find these supplements online. Now, let me offer a general caution about supplements. The FDA does not monitor and regulate supplements in the same way they do for medications. Furthermore, if you purchase a supplement from a seller, make sure you know what you are buying.

Some independent groups have tested certain supplements and found they do not always contain the same ingredients listed on the bottle. If ASU’s are prescribed for osteoarthritis in the future, it will be important that they go through the proper testing to become an FDA regulated medication.

Lastly, always discuss supplements you are taking with your doctor and registered dietitian. If you would like to learn more about improving your symptoms from osteoarthritis, meet with your registered dietitian.


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Dustin Moore, MS, RD
My name is Dustin Moore and I'm a registered dietitian, lecturer and program director for a dietetic internship. I received my bachelor's degree in dietetics from Brigham Young University (BYU) and completed my master's degree and dietetic internship at California State University (CSU) Long Beach. In addition to teaching undergraduate courses at CSU Long Beach, I've also worked as an outpatient dietitian specializing in gastric disorders. Education of individuals - whether it's patients, students, dietetic interns, or the general population - gives me direction and drive. Whatever is related to the wellness and longevity in the life of individuals is something I'm interested in teaching and discussing. My role as a dietitian centers on the question of "What is the purpose of having good health?" And I believe the answer to that is to maximize the freedom there is to life! In resolving health issues and struggles, people are granted great freedom which allows them to pursue life to it's fullest. Of course, I love cooking! I also love spending time with family and loved ones, writing, and teaching. But, when I'm not playing the role of the food snob, I also enjoy sports, weight training, archery and generally working with my hands on projects around the house.