Restasis® vs Xiidra®: Here’s What You Need To Know

Let’s talk about the pros and cons of each medication

NEW Restasis Multidose
Source: Restasis.com

Restasis® Pros:

  • Restasis® has been FDA approved for over a decade. Therefore, most eye doctors have a lot of experience with the medication and subsequent side effects.
  • There are two different ways to receive this medication. One option is single-use individual vials. The other is the new Restasis® MultiDose™ bottle (shown above). Some patients feel this bottle is easier to use.

Restasis® Cons:

  • Restasis® usually takes 3 months or longer for patients to feel an improvement in their symptoms.
  • Depending on your insurance coverage, it can be expensive (although there is a rebate card available).
  • Restasis® can cause burning when putting the drop in.
Xiidra iinsider card
Source: Xiidra.com

Xiidra® Pros:

  • There can be improvements in symptoms in as early as two weeks.
  • With the Xiidra® rebate card, the first month of Xiidra® is free. This allows you to try out the medication to see if it’s working. 

Xiidra® Cons:

  • Depending on your insurance coverage, it can be expensive (although there is a rebate card available from your eye doctor).
  • It can cause irritation and a strange taste in your mouth. This unusual taste bothers some patients more than others.

Thankfully, we now have two medications that can help patients with dry eye! Wondering if you’re a candidate for Restasis® or Xiidra®? Talk to your eye care professional for more information.

 Restasis®Xiidra®
Dosing?One drop twice a day approximately 12 hours apart. One drop twice a day approximately 12 hours apart.
FDA approved?20022016
Common side effects?Burning with putting in the drop, redness, and blurry vision.Eye irritation, discomfort or blurred vision, and an unusual taste sensation.
When do symptoms start to improve?Roughly 3 months. Can be as early as 2 weeks.
Cost? Depends on insurance but Restasis® does offer a rebate card card.Depends on insurance but Xiidra® does offer a rebate card that gives you the first month for free.

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